易钢

■ 基本信息

易钢、男、1964年4月出生、硕士、教授、硕士生导师。


■ 联系方式

重庆医科大学检验医学院、临床检验诊断学教育部重点实验室,400016

电子邮箱:yigang666@cqmu.edu.cn


■ 学习与工作经历

1982.09-1986.07 重庆大学化学系,本科

1986.07-1993.05 重庆医科大学医学检验系,助教

1993.05-2007.09 重庆医科大学医学检验系,讲师

2004.02-2006.06 重庆医科大学医学检验系,硕士

2007.07-2017.07 重庆医科大学检验医学院,副教授

2017.07-至今   重庆医科大学检验医学院,教授

2005.05-至今   临床检验诊断学教育部重点实验室


■ 研究方向

1. 生物分析化学方向;

2. 生物传感和纳米技术方向。


■ 科研项目

1. 2020年度市教委科学技术研究计划重点课题,KJZD-K202000404,“基于DNA四面体修饰的树枝状杂交链信号放大反应超灵敏检测DNA甲基化”5万,2020.10-2023.10,在研,主持。

2. 重庆市渝中区科委基础研究与前沿探索项目,20180127,“基于3-D DNA walker和超分支滚环扩增(HRCA)的通用型检测新方法的研究”,2018.10-2021.10,已结题,主持。


■ 学术论著

1. Zuowei Xie, Siyi Chen, Wenxiu Zhang, Shuhui Zhao, Zixin Zhao, Xingyu Wang, Yuqi Huang,Gang Yi*. A novel fluorescence amplification strategy combining cascade primer exchange reaction with CRISPR/Cas12a system for ultrasensitive detection of RNase H activity. Biosensors and Bioelectronics, 2022;206:114-135.(通讯作者2022 IF=12.545)

2. Zuowei Xie1, Xingyu Wang1, Siyi Chen, Zixin Zhao, Shuhui Zhao, Wenxiu Zhang, Lijuan Luo, Gang Yi*. Construction of a simple, localized and homogeneous fluorescence detection platform for T4 PNK activity based on tetrahedral DNA nanostructure-mediated primer exchange reaction.Microchemical Journal, 2022, 183:107989(通讯作者2022 IF=5.304)

3. Wenxiu Zhang, Shuhui Zhao, Zuowei Xie, Siyi Chen, Yuqi Huang, Zixin Zhao,Gang Yi.The fluorescence amplification strategy based on 3D DNA walker and CRISPRCas-12a for the rapid detection of BRAF V600E. Analytical Sciences.2022;38:1057-1066(通讯作者2022 IF=2.081)

4. Yuqi Huang, Wenxiu Zhang, Shuhui Zhao, Zuowei Xie, Siyi Chen, Gang Yi.Ultra-sensitive detection of DNA N6-adenine methyltransferase based on a 3D tetrahedral fluorescence scaffold assisted by symmetrical double-ring dumbbells.Analytica Chimica Acta.2021;11:1-8;(通讯作者2021IF=6.558)

5. Yuqi Huanga,Shuhui Zhaoa,Wenxiu Zhanga, Qiuyue Duana, Qi Yana, Hu Fub, Liang Zhonga and Gang Yi*Multifunctional electrochemical biosensor with “tetrahedral tripods” assisted multiple tandem hairpins assembly for ultra-sensitive detection of target DNA.RSC Advances. 2021; 11:20046–200569(通讯作者2021IF=3.361)

6. 周春燕,范婷婷,易钢*. miR-1271抑制卵巢癌细胞的增殖和转移的研究[J].中国临床药理学杂志,2021;14 (37):1811-1815(通讯作者CSCD)

7. Gang Yi* , Qiuyue Duan*, Qi Yan*, Yuqi Huang*,Wenxiu Zhang*, and Shuhui Zhao* Polymerase/Nicking Enzyme Powered Dual-Template Multi-Cycle G-Triplex Machine for HIV-1 Determination. Analytical Sciences. 2021;8(37):1087-1093(通讯作者2021IF=2.081)

8. 李彦黎,李晋,王姚,王维,易钢*.稳定态胰岛素抵抗指数、性激素、糖代谢指标对诊断多囊卵巢综合征的效能分析[J].中国妇产科临床杂志,2020;6 (21):631-633(通讯作者2020 CSCD)

9. Changjing Yuan, Jie Fang, Qiuyue Duan, Qi Yan, Jing Guo, Taixian Yuan, Gang Yi*.Two-layer three-dimensional DNA walker with highly integrated entropy-driven and enzyme-powered reactions for HIV detection.Biosensors and Bioelectronics, 2019;133:243-249(通讯作者2019IF=10.257)


■ 专利授权

获得授权国内发明专利1项

易钢,付虎,葛闯。一种基于适体的微流控化学发光芯片及其制备方法。中国发明专利ZL201210339160.X.授权日期2015.6.30


信息来源:https://jyx.cqmu.edu.cn/info/1093/2385.htm